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129 Activation of the p53 Pathway by RG7112 Enhances Antitumor Effect of Androgen Deprivation and Docetaxel in Prostate Cancer Cells in Vivo

โœ Scribed by Higgins, B.; Kolinksy, K.; Filipovic, Z.; Tovar, T.; Zhang, Y.; Packman, K.; Vassilev, L.


Book ID
123066097
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
61 KB
Volume
48
Category
Article
ISSN
0959-8049

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## Abstract Increasing evidence suggests that androgen independent prostate cancer (PC) maintains a functional androgen receptor (AR) pathway despite the low levels of circulating androgen following androgen withdrawal, the molecular mechanisms of which are not well defined yet. To address this que