✦ LIBER ✦

1272 POTENTIAL IMMUNOTHERAPEUTIC APPLICATIONS OF PHOSPHODIESTERASE INHIBITION FOR PROSTATE CANCER

✍ Scribed by Siemens, David; Hamilton, Tom; Gjoncaj, Klodiana; Hu, Nianping; Bell, Erin; Graham, Charles

Book ID: 123486007
Publisher: Lippincott Williams and Wilkins
Year: 2011
Tongue: English
Weight: 91 KB
Volume: 185
Category: Article
ISSN: 0022-5347
DOI: 10.1016/j.juro.2011.02.958

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## Abstract Prostate cancer cells are generally dependent on androgen stimulation mediated by the androgen receptor (AR) for growth and survival, and, therefore, hormonal manipulation, such as castration and/or the use of AR antagonists, results in a regression of the cancer. However, this treatmen