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127 Preconditioning C3A cells for usage in bioartificial liver support systems

✍ Scribed by C. Filippi; S. Keatch; D. Rangar; P.C. Hayes; J.N. Plevris


Book ID
117372957
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
61 KB
Volume
40
Category
Article
ISSN
0168-8278

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## Abstract Extrahepatic bioartificial liver devices should provide an intact urea cycle to detoxify ammonia. The C3A cell line, a subclone of the hepatoma‐derived HepG2 cell line, is currently used in this context as it produces urea, and this has been assumed to be reflective of ammonia detoxific