126 Amplification of different MYC-family genes in small cell lung carcinoma (SCLC) cell lines derived from one patient
โ Scribed by Klaas Kok; Johan de Vries; Annemarie H. van der Hout; Henk H. Berendsen; Lous de Leij; Charles H.C.M. Buys
- Book ID
- 119104516
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 85 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0165-4608
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๐ SIMILAR VOLUMES
We identified 126 tumor cell lines established from patients with small cell cancer at the NCI-Navy Medical Oncology Branch from 1977 through 1992. Extensive clinical information was available on 96 patients from whom these cell lines were established. These patients comprised approximately one four
In a small-cell lung carcinoma (SCLC) tumor specimen as well as in 3 cell lines derived from SCLC biopsies obtained from the same patient at successive times during the clinical course, either the N-myc gene or the c-myc gene appeared to be amplified and expressed. The initial tumor specimen, a lymp