✦ LIBER ✦
125I-EGF binding to responsive and nonresponsive cells in culture: Loss of cell-associated radioactivity relates to growth induction
✍ Scribed by R. Paul Schaudies; Robert A. Harper; C. Richard Savage Jr.
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 713 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
✦ Synopsis
A comparison of the binding and overall processing of epidermal growth factor (EGF) was made in ten mammalian fibroblast-like and three epitheliallike cell lines. EGF stimulated the growth of five fibroblastic cell lines (132 to 224%) after 10 days in the constant presence of EGF and were termed "responsive". Eight of the lines did not respond or were growth inhibited by EGF