1,25 Dihydroxyvitamin D3is required for growth-independent expression of alkaline phosphatase in cultured rat osteoblasts
✍ Scribed by Janine Fritsch; Brigitte Grosse; Michèle Lieberherr; Sonia Balsan
- Book ID
- 110554289
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 663 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1432-0827
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To evaluate the osteoblastic function in patients with multiple pituitary hormone deficiencies (M-PHD) and with isolated growth hormone deficiency (I-GHD), bone cells were cultured and the effects of lo-' M 1,25-dihydroxyvitamin D, (1,25 [OH],D,) on parameters of cell proliferation, osteoblastic dif
The effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) (2.3 x 10(-12) - 1.4 x 10(-6) [M]) on alkaline phosphatase, collagen, and cell proliferation were examined in primary cultured hypertrophic chondrocytes prepared from the distal epiphyseal growth plate of the tibias of 12-day chick embryos. 1,25(