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1,25-Dihydroxyvitamin D3 regulates PTHrP expression via transcriptional, post-transcriptional and post-translational pathways

✍ Scribed by Vandanajay Bhatia; Ramanjaneya V. Mula; Miriam Falzon

Book ID: 116735033
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 714 KB
Volume: 342
Category: Article
ISSN: 0303-7207
DOI: 10.1016/j.mce.2011.05.025

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## Abstract CCAAT/enhancer binding protein δ (C/EBPδ) plays a key role in mammary epithelial cell G~0~ growth arrest. C/EBPδ gene expression is down‐regulated in rodent mammary tumorigenesis and in human breast cancer, suggesting that “loss of function” alterations in C/EBPδ gene expression are com