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1,25-dihydroxyvitamin D3-induced apoptosis of retinoblastoma cells is associated with reciprocal changes of Bcl-2 and bax

✍ Scribed by Nicole Wagner; Kay-Dietrich Wagner; Gunnar Schley; Lucia Badiali; Heinz Theres; Holger Scholz


Book ID
117100189
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
427 KB
Volume
77
Category
Article
ISSN
0014-4835

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✍ Lawrence E. Harrison; Qing Mei Wang; George P. Studzinski πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 233 KB πŸ‘ 1 views

Cellular differentiation of neoplastic cells after exposure to 1,25-dihydroxyvitamin D 3 (1,25 D 3 ) is accompanied by altered cell cycle regulation. In previous studies, blocks in both G 1 /S and G 2 /M checkpoints have been observed in 1,25D 3 -treated HL60 cells, but the mechanism of the 1,25D 3