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1,25-Dihydroxyvitamin D3 increases the toxicity of hydrogen peroxide: the role of calcium and heat shock

โœ Scribed by Stephen M. Krane; Barbara S. Polla; Joseph V. Bonventre

Book ID
113371139
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
632 KB
Volume
25
Category
Article
ISSN
0531-5565

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1,25 dihydroxyvitamin D3 enhances the ca
1,25 dihydroxyvitamin D3 enhances the calcium response of keratinocytes
โœ Anita V. Ratnam; Daniel D. Bikle; Jin-Kook Cho ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 250 KB

The steroid hormone 1,25 dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ) regulates cell proliferation and differentiation. Intracellular calcium (Cai) concentrations play a crucial role in these events. From our previous studies, we have demonstrated a calcium receptor (CaR) in keratinocytes which appears to