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1,25-Dihydroxyvitamin D3 enhances the growth of tumors in athymic mice inoculated with receptor rich osteosarcoma cells

✍ Scribed by Kanji Yamaoka; Samuel L. Marion; Alfred Gallegos; Mark R. Haussler


Book ID
117057123
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
387 KB
Volume
139
Category
Article
ISSN
0006-291X

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It is well known that 17 beta-estradiol (E2) and 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) have important roles in bone metabolism. This study was undertaken to examine E2 regulation of 1,25(OH)2D3 receptor (VDR) expression and the biological action of 1,25(OH)2D3 in human osteoblast-like cells. When h