1,2,4-Triazole Analogs of Histamine
β Scribed by Ainsworth, C.; Jones, R. G.
- Book ID
- 118173261
- Publisher
- American Chemical Society
- Year
- 1953
- Tongue
- English
- Weight
- 571 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
## Abstract The synthesis of 1,2,4βtriazole and thiazole analogs of ketoconazole is described in which one of the Ξ± azole ring carbons is linked to Cβ2 of the ketal by means of a three methylene tether. Lithiation of 1βmethylβ1,2,4βtriazole and thiazole and subsequent alkylation with 2β(2,4βdichlor
## Abstract The mass spectra of monomethyl 1,2,4βtriazoles contain fragment ions produced by specific cleavage of the heterocyclic ring. A major fragmentation from many molecular ions involves the elimination of HCN, but loss of N~2~ is either very small or completely absent. No N or H scrambling o