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1233 GS-6620: A LIVER TARGETED NUCLEOTIDE PRODRUG WITH POTENT PAN-GENOTYPE ANTI-HEPATITIS C VIRUS ACTIVITY IN VITRO

โœ Scribed by Ray, A.S.; Feng, J.Y.; Wang, T.; Wong, K.; Zhang, L.; Babusis, D.; Vela, J.; Butler, T.; Xu, J.; Aktoudianakis, V.; Lee, R.; Sauer, D.; Henne, I.; Fenaux, M.; Mo, H.; Zhong, W.; Metobo, S.; Perry, J.; Kim, C.; Cho, A.


Book ID
122503678
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
40 KB
Volume
54
Category
Article
ISSN
0168-8278

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## Anti -hepatitis C virus (HCV) drug development has been challenged by a lack of experience with inhibitors inclusive of in vitro, animal model, and clinical study. This manuscript outlines activity and correlation across such a spectrum of models and into clinical trials with a novel selective