✦ LIBER ✦

1.2.2 USING STEM CELLS AND IPS CELLS TO DISCOVER NEW TREATMENTS FOR PARKINSON'S DISEASE

✍ Scribed by O. Cooper; P. Hallett; O. Isacson

Book ID: 117754450
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 55 KB
Volume: 18
Category: Article
ISSN: 1353-8020
DOI: 10.1016/s1353-8020(11)70079-7

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Using stem cells and iPS cells to discov

Using stem cells and iPS cells to discover new treatments for Parkinson's disease

✍ Oliver Cooper; Penny Hallett; Ole Isacson 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 227 KB

Parkinson's disease genetic mutations in

Parkinson's disease genetic mutations increase cell susceptibility to stress: Mutant α-synuclein enhances H2O2- and Sin-1-induced cell death

✍ Haibing Jiang; Yen-Ching Wu; Masayuki Nakamura; Yideng Liang; Yuji Tanaka; Susan 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 298 KB

Nerve growth factor prevents 1-methyl-4-

Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: Relevance to therapeutical application for parkinson's disease

✍ Koji Shimoke; Hiroaki Chiba 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 1 views

Nerve growth factor (NGF) mediates a variety of nerve cell actions through receptor tyrosine kinase TrkA. It has been revealed that the Akt pathway contributes to the prevention of apoptosis. It is thought that Parkinson's disease involves apoptosis, and NGF prevents apoptosis in an in vivo model sy

Expression and functional analysis of G1

Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells

✍ Neganova, I; Zhang, X; Atkinson, S; Lako, M 📂 Article 📅 2008 🏛 Nature Publishing Group 🌐 English ⚖ 685 KB

Dopamine agonists used in the treatment

Dopamine agonists used in the treatment of Parkinson's disease and their selectivity for the D1, D2, and D3 dopamine receptors in human striatum

✍ Jacques De Keyser; Jean-Paul De Backer; Nadine Wilczak; Luc Herroelen 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 539 KB

Activation of the extracellular signal-r

Activation of the extracellular signal-regulated kinases 1 and 2 by glial cell line-derived neurotrophic factor and its relation to neuroprotection in a mouse model of Parkinson's disease

✍ Niklas Lindgren; Rehana K. Leak; Kirsten M. Carlson; Amanda D. Smith; Michael J. 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 851 KB

## Abstract Glial cell line‐derived neurotrophic factor (GDNF) has been shown to be neuroprotective in animal models of the dopamine deficiency in Parkinson's disease. To examine the role of the extracellular signal‐regulated kinases 1 and 2 (ERK1/2) in this process, we infused a single dose of GDN