1217 Tumor necrosis factor appear the neuroprotection through the enhancement of transient outward potassium currents in cultured rat cortical neurons

Tumor necrosis factor enhancement of tra

Tumor necrosis factor enhancement of transient outward potassium currents in cultured rat cortical neurons

✍ Hideki Houzen; Seiji Kikuchi; Morio Kanno; Kazuyoshi Shinpo; Kunio Tashiro 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 2 views

The effect of recombinant human tumor necrosis factor-alpha (TNF) on voltage-gated membrane currents of cultured neurons derived from embryonic rat cerebral cortex was studied using the whole-cell patch-clamp technique. Treatment of neurons with TNF resulted in an increase in outward potassium curre