𝔖 Bobbio Scriptorium
✦   LIBER   ✦

1206 POSTER A study of familial melanoma in greece and identification of germline mutations in the CDKN2A tumour suppressor gene


Book ID
123312787
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
141 KB
Volume
3
Category
Article
ISSN
1359-6349

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Screening of germline mutations in the C
✍ Anton Platz; Johan Hansson; Ulrik Ringborg πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 61 KB πŸ‘ 2 views

Germline mutations within the CDKN2A gene, coding for the cyclin-dependent kinase inhibitor p16, have been detected by screening in 8% of Swedish families with an inheritance of cutaneous melanoma (FMM) and dysplastic nevus syndrome (DNS). Contrastingly, the closely related gene CDKN2B had no diseas

Identification of modifier genes for cut
✍ Xiaohong Rose Yang; Ruth M. Pfeiffer; William Wheeler; Meredith Yeager; Stephen πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 86 KB

## Abstract __CDKN2A__ is a major susceptibility gene for cutaneous malignant melanoma (CMM), but the variable penetrance and clinical manifestations among mutation carriers suggest the existence of modifier factors. The goal of this study was to identify modifier genes for CMM in CMM‐prone familie

New founder germline mutations of CDKN2A
✍ Caroline Kannengiesser; StΓ©phane Dalle; Marie-ThΓ©rΓ¨se Leccia; Marie FranΓ§oise Av πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 372 KB πŸ‘ 1 views

## Abstract Germline mutations in the __CDKN2A__ gene have been shown to predispose individuals to cutaneous malignant melanoma. Here, we describe three melanoma‐prone families and one isolated patient affected by multiple melanoma who carried a tandem germline mutation of __CDKN2A__ at the nucleot