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1,2-Diacylglycerol content in myocardium from spontaneously hypertensive rats during the development of hypertension

✍ Scribed by J. Kondo; Y. Yamada; K. Okumura; H. Hashimoto; T. Ito; T. Satake


Book ID
115981420
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
97 KB
Volume
22
Category
Article
ISSN
0022-2828

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There is evidence that cardiac hypertrophy in spontaneously hypertensive rats (SHR) occurs before the development of hypertension. 1,2-Diacylglycerol, which is thought to be a second messenger activating protein kinase C, is also produced in excess in SHR hearts at 4 weeks of age, before established