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11β-Hydroxysteroid Dehydrogenases in the Brain : Two Enzymes Two Roles

✍ Scribed by MEGAN C. HOLMES; JOYCE L.W. YAU; YURI KOTELEVTSEV; JOHN J. MULLINS; JONATHAN R. SECKL


Book ID
111476978
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
741 KB
Volume
1007
Category
Article
ISSN
0890-6564

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Biochemical conditions regulating the llfi-hydroxysteroid dehydrogenase activity in spleen homogenate of mice have been studied. The conversion of ll-hydroxy-to ll-dehydrosteroids is a reversible reaction. The ratio of these compounds at equilibrium and the reaction rates depend on the pH and on the