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11β-Hydroxy-progesteron-18-säure-lacton und die WALDEN'sche Umkehrung am Kohlenstoffatom 11 bei 18-oxygenierten Steroiden. Über Steroide, 178. Mitteilung

✍ Scribed by K. Heusler; P. Wieland; A. Wettstein


Publisher
John Wiley and Sons
Year
1961
Tongue
German
Weight
512 KB
Volume
44
Category
Article
ISSN
0018-019X

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✦ Synopsis


The intramolecular nucleophilic displacement with WALDEN inversion of the llα‐tosyloxy group in 18,20‐lactones of the pregnane series is described. Depending upon the reaction conditions 18,11,β‐lactones or orthoester derivatives are obtained.