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[11C]Methylation on a C18 Sep-Pak cartridge: a convenient way to produce [N-methyl-11C]choline

✍ Scribed by Claudio Pascali; Anna Bogni; Ren Itawa; Mara Cambiè; Emilio Bombardieri

Publisher
John Wiley and Sons
Year
2000
Tongue
French
Weight
256 KB
Volume
43
Category
Article
ISSN
0022-2135

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## Abstract [__N__‐Methyl‐^11^C]choline has been synthesized at room temperature by the reaction of [^11^C]CH~3~I with 2‐dimethylaminoethanol (DMAE), with the latter directly loaded on a weak cation‐exchange cartridge. Most of the efforts have been directed to reduce the amount of residual precurso