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[11C]GSK2126458 and [18F]GSK2126458, the first radiosynthesis of new potential PET agents for imaging of PI3K and mTOR in cancers

✍ Scribed by Min Wang; Mingzhang Gao; Kathy D. Miller; George W. Sledge; Qi-Huang Zheng


Book ID
113496568
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
338 KB
Volume
22
Category
Article
ISSN
0960-894X

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## Abstract The tubulin polymerization is an attractive target for anticancer therapy and in the development of cancer imaging agents for use in biomedical imaging technique positron emission tomography (PET). 7‐Aroyl‐aminoindoline‐1‐sulfonamides are a novel class of potent antitublin agents. Carbo