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11C-Labeled ketanserin: A selective serotonin S2 antagonist

✍ Scribed by M. Berridge; D. Comar; C. Crouzel; J-C. Baron

Publisher: John Wiley and Sons
Year: 1983
Tongue: French
Weight: 245 KB
Volume: 20
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580200110

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## Abstract We demonstrated the synthesis of carbon‐11 labeled 17‐__α__‐hydroxy‐11‐__β__‐/4‐/[methyl]‐[1‐methylethyl]‐aminophenyl/‐17__α__‐[prop‐1‐ynyl]esta‐4‐9‐diene‐3‐one (RU40555), a selective glucocorticoid receptor (GR) antagonist, and examined the __in vivo__ profile of [^11^C]RU40555. [^11^