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11C-2-Deoxy-d-glucose: synthesis and preliminary comparison with11C-d-glucose as a tracer for cerebral energy metabolism in PET studies

✍ Scribed by Sharon Stone-Elander; J. Lars G. Nilsson; Gunnar Blomqvist; Erling Ehrin; Lars Eriksson; Birgit Garmelius; Torgny Greitz; Peter Johnström; Irene Sjögren; Lennart Widén


Publisher
Springer
Year
1985
Tongue
English
Weight
741 KB
Volume
10-10
Category
Article
ISSN
0340-6997

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3-[11C]-methyl-D-glucose, a potential ag
✍ G. Kloster; C. Müller-Platz; P. Laufer 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 311 KB

## Abstract 3‐[^11^C]‐Methyl‐D‐glucose was synthetized by methylation via ^11^CH^3^I of the potassium salt of diacetone‐D‐glucose; hydrolysis of the ketal groups with HCl yields 3‐[^11^C]‐methyl‐D‐glucose. The radiochemical yield is 35% at a specific activity of 1.9 mCi/μmole. Synthesis time includ