Validation of a sensitive and specific r
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R.B. Takkenberg; H.L. Zaaijer; R. Molenkamp; S. Menting; V. Terpstra; C.J. Weegi
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Article
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2009
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John Wiley and Sons
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English
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## Abstract Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) serves as a template for viral replication and plays a role in persistence of HBV infection. The origin and significance of cccDNA in plasma however, is not well understood. A sensitive, specific, and reproducible realโtime