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1176 A sensitive, quantitative real-time PCR assay to detect lamivudine resistance-associated mutations in hepatitis B virus (HBV)

โœ Scribed by LEWIN, S; WHITEMAN, F; BOWDEN, S; AYRES, A; WALTERS, T; LOCARNINI, S; LAU, D


Book ID
123360762
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
146 KB
Volume
38
Category
Article
ISSN
0270-9139

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## Abstract Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) serves as a template for viral replication and plays a role in persistence of HBV infection. The origin and significance of cccDNA in plasma however, is not well understood. A sensitive, specific, and reproducible realโ€time