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1166 THE PREDICTIVE VALUE OF IL28B GENE POLYMORPHISM FOR RESPONSE TO PEGINTERFERON AND RIBAVIRIN IS ENHANCED BY QUANTITATION OF IP-10 IN PRETREATMENT SERUM

✍ Scribed by Fried, M.W.; Aerssens, J.; Thompson, A.; Darling, J.; McHutchison, J.G.; Howell, C.; Afdhal, N.; Bollekens, J.; DeWit, M.; Scholliers, A.; Shianna, K.; Goldstein, D.; Fanning, G.


Book ID
122731232
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
51 KB
Volume
52
Category
Article
ISSN
0168-8278

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Quantitation of pretreatment serum inter
✍ Jama M. Darling; Jeroen Aerssens; Gregory Fanning; John G. McHutchison; David B. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 579 KB

Polymorphisms of the IL28B gene are highly associated with sustained virological response (SVR) in patients with chronic hepatitis C treated with peginterferon and ribavirin. Quantitation of interferon-c-inducible protein-10 (IP-10) may also differentiate antiviral response. We evaluated IP-10 level