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1148 EFFECT OF THE IL28B SINGLE NUCLEOTIDE POLYMORPHISM (SNP) ON THE FIRST PHASE HEPATITIS C VIRUS KINETICS IN PATIENTS TREATED WITH PEG-INTERFERON AND RIBAVIRIN (PR)

✍ Scribed by Durante-Mangoni, E.; Pinto, D.; Battimelli, C.; Farinaro, V.; Savinelli, C.; Senese, A.; Iorio, V.; Graziano, C.; Iossa, D.; Molaro, R.; Sodano, G.; Utili, R.

Book ID: 122907531
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 54 KB
Volume: 58
Category: Article
ISSN: 0168-8278
DOI: 10.1016/S0168-8278(13)61149-6

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## Abstract It has been reported that genetic polymorphisms near the __IL28B__ gene or amino acid substitutions in hepatitis C virus (HCV) core protein are associated with the clinical outcome of peginterferon (PEG‐IFN) and ribavirin combination therapy. The impact of these factors on the pure sens