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1141636674 Differential serine and tyrosine phosphorylation of Signal Transducer and Activator of Transcription 3 (STAT3) in Jeg-3 choriocarcinoma cell lines

โœ Scribed by J Roediger; S Busch; A Enkelmann; TG Poehlmann; UR Markert


Book ID
110107870
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
51 KB
Volume
55
Category
Article
ISSN
8755-8920

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## Abstract Signal transducer and activator of transcription 3 (Stat3) is one of a family of cytoplasmic proteins that participate in normal cellular responses to cytokines and growth factors as transcription factors. Stat3 modulates various physiological functions including cell survival, cellโ€cyc

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## Abstract Stat3 expression in cancer may have important prognostic and therapeutic value, but there has been no reports correlating Stat3 expression with prognosis in patients with osteosarcoma. The goal of this study is to correlate patient prognosis with the expression of Stat3 in osteosarcoma