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113 Novel small-molecule inhibitors of Interleukin-6 (IL-6) signalling

✍ Scribed by M. Haque; G. Zinzalla; B.P. Basu; J. Anderson; S. Haider; F. Hasan; D. Antonow; D. Morgenstern; S. Neidle; D.E. Thurston

Book ID: 119602795
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 55 KB
Volume: 8
Category: Article
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(10)71818-8

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## Abstract The unicellular __Tetrahymena__ and its medium contain immunoreactively interleukin 6 (IL‐6)‐like molecules (hereinafter IL‐6) in a measurable quantity in the 24 h‐old cultures. This protozoan takes up exogenously supplied IL‐6 very quickly, and this can be found in similar amounts in b