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1128 Effect of alcohol consumption on CYP2E1 and CYP3A activities in humans: insight into acetaminophen hepatotoxicity in alcoholics

✍ Scribed by LIANGPUNSAKUL, S; GORSKI, C; CRABB, D; HALL, S; CHALASANI, N


Book ID
122824529
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
163 KB
Volume
38
Category
Article
ISSN
0270-9139

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Activity of CYP2E1 and CYP3A enzymes in
✍ Suthat Liangpunsakul; Dhanashri Kolwankar; Amar Pinto; J. Christopher Gorski; St πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 227 KB πŸ‘ 1 views

Alcohol consumption is known to induce hepatic CYP2E1 activity, but its effect on hepatic and intestinal CYP3A in humans is not known. We have conducted a study to compare the CYP2E1 and CYP3A activities in 20 individuals with moderate alcohol consumption and 20 gender-, race-. and body mass index (