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111In-tropolonate labelled platelets; studies in normals and in patients with thrombocytopenia

✍ Scribed by H. Louwes; H. Beekhuis; W. Th. Goedemans; S. P. Keijser; J. J. Schuurman

Publisher
Springer
Year
1987
Tongue
English
Weight
428 KB
Volume
13
Category
Article
ISSN
0340-6997

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✦ Synopsis

Human platelets were labelled with aqueous 111In-tropolonate in comparison with 111In-oxinate. In normals the labelling efficiency with 111In-tropolonate was higher (93% +/- 2%) than with 111In-oxinate (67% +/- 8%) (P less than 0.05). In cases of severe thrombocytopenia, lower labelling efficiencies were obtained. In six normals a mean platelet life of 9 days +/- 3 days and an initial recovery of 59% +/- 15% were obtained. In twelve patients with thrombocytopenia the mean platelet life was 4 days +/- 4 days and the initial recovery was 58% +/- 20%. The absolute uptake of radioactivity in spleen and in liver in both groups are reported.

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Detection of platelet consumption in aor
Detection of platelet consumption in aortic graft with111In-labeled platelets
✍ Tokuo Yui; Tatsumi Uchida; Shin Matsuda; Kyoko Iwaya; Masaji Umino; Kazuo Ono; S πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 247 KB

Increased platelet consumption in two patients with aortic graft was detected by scintiphotography using 111In-labeled autologous platelets. There was shortened platelet survival time in these patients. These findings might suggest that platelet consumption in aortic prosthesis is related to thrombo