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11-Hydroxy-4-methyl-2,4,6-dodecatrienoic acid from fermentations of a Mucor species

โœ Scribed by Kirsten Lorenzen; Timm Anke; Olov Sterner

Book ID
103345834
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
161 KB
Volume
43
Category
Article
ISSN
0031-9422

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โœ Roland M. Wenger ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 948 KB

## Abstract Starting from __R__,__R__โ€(+)โ€tartaric acid, the synthesis of (2__S__,3__R__,4__R__6__E__)โ€3โ€hydroxy โ€4โ€methylโ€2โ€methylaminoโ€6โ€octenoic acid in 24 steps is reported. This novel amino acid is found in the cyclic undecapeptide cyclosporin A, isolated from the fungal strain __Tolypocladium