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11-Dehydrothromboxane B2: A Quantitative Index of Thromboxane A2Formation in the Human Circulation

✍ Scribed by Francesca Catella, Dean Healy, John A. Lawson and Garret A. FitzGerald

Book ID: 123633180
Publisher: National Academy of Sciences
Year: 1986
Tongue: English
Weight: 800 KB
Volume: 83
Category: Article
ISSN: 0027-8424
DOI: 10.2307/28053

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Thromboxane A2, a potent vasoconstrictor and platelet agonist, is an evanescent cyclooxygenase product of arachidonic acid. Assessment of thromboxane biosynthesis commonly relies upon analysis of the stable but biologically inactive hydration product, thromboxane B2. However, measurement of this com