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1096 DENDRITIC CELLS BUT NOT KUPFFER CELLS ARE REQUIRED FOR THE ACTIVATION OF SELF-REACTIVE CD8 T-CELLS IN THE LIVER

✍ Scribed by Eickmeier, I.; Derkow, K.; Müller, A.; Seidel, D.; Bergk, A.; Wiedenmann, B.; Schott, E.


Book ID
122732937
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
54 KB
Volume
52
Category
Article
ISSN
0168-8278

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The immune response to foreign antigens in the liver is often suboptimal and this is clinically relevant in chronic persistence of hepatotropic viruses. In chronic infection with the hepatitis C virus, activated CD8؉ T cells specific for viral epitopes are present in the peripheral blood and the liv