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109 HEPATITIS B VIRUS RESTRAINS ACTIVATION OF SPECIFIC INTERFERON RESPONSIVE GENES IN HUMAN HEPATOCYTES REPOPULATING THE LIVER OF UPA/SCID MICE

✍ Scribed by T. Bornscheuer; T. Volz; M. Lütgehetmann; A.W. Lohse; J.H. Bockmann; J. Petersen; M. Dandri

Book ID: 117378197
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 49 KB
Volume: 52
Category: Article
ISSN: 0168-8278
DOI: 10.1016/s0168-8278(10)60111-0

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## Abstract Studies of hepatitis B virus (HBV) infection in non‐human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV inf