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108 Cloning and distribution of the mechanosensory-like gene expressed in the rat nervous system

✍ Scribed by Yuki Minami; Kiyoshi Inoue; Hiroyuki Morimura; Shoichi Shimada


Book ID
119130104
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
101 KB
Volume
25
Category
Article
ISSN
0168-0102

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Urocortin was recently cloned from the rat midbrain. Urocortin is a member of the corticotropin releasing factor (CRF) peptide family and shows 45% sequence identity to CRF and 63% sequence identity to urotensin. It binds with a high affinity to CRF 1 and CRF 2 receptors, resulting in the stimulatio