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1059 CRITICAL ROLE OF TNF-RECEPTOR 1 BUT NOT 2 IN HEPATIC STELLATE CELL PROLIFERATION, EXTRACELLULAR MATRLX REMODELING AND LIVER FIBROGENESIS

✍ Scribed by Tarrats, N.; Moles, A.; Morales, A.; Garcia-Ruiz, C.; Fernandez-Checa, J.; Mari, M.

Book ID
122184131
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
41 KB
Volume
54
Category
Article
ISSN
0168-8278

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Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis
✍ Núria Tarrats; Anna Moles; Albert Morales; Carmen García-Ruiz; José C. Fernández 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 606 KB

Tumor necrosis factor (TNF) has been implicated in the progression of many chronic liver diseases leading to fibrosis; however, the role of TNF in fibrogenesis is controversial and the specific contribution of TNF receptors to hepatic stellate cell (HSC) activation remains to be established. Using H