𝔖 Bobbio Scriptorium
✦   LIBER   ✦

1055 ANTIVIRAL ACTIVITY OF ANA598, A POTENT NON- NUCLEOSIDE POLYMERASE INHIBITOR, IN CHRONIC HEPATITIS C PATIENTS

✍ Scribed by Lawitz, E.; Rodriguez-Torres, M.; DeMicco, M.; Nguyen, T.; Godofsky, E.; Appleman, J.; Rahimy, M.; Crowley, C.; Freddo, J.


Book ID
122449045
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
45 KB
Volume
50
Category
Article
ISSN
0168-8278

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Antiviral activity of the hepatitis C vi
✍ Frank Wagner; Robert Thompson; Constantino Kantaridis; Paul Simpson; Philip J. F πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 599 KB

More effective and better-tolerated therapies are needed for chronic hepatitis C virus (HCV) infection. Among the direct-acting anti-HCV agents in development is the nonstructural 5B protein (NS5B polymerase) non-nucleoside inhibitor filibuvir. We investigated the antiviral activity, pharmacokinetic

Robust antiviral activity of R1626, a no
✍ Stuart K. Roberts; Graham Cooksley; Gregory J. Dore; Richard Robson; David Shaw; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 511 KB

The nucleoside analog R1479 is a potent and highly selective inhibitor of nonstructural protein 5B-directed hepatitis C virus (HCV) replication in vitro. R1626, a tri-isobutyl ester prodrug of R1479, was developed to increase bioavailability and improve antiviral activity. A multicenter, observer-bl