Correlation between functional and molec
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H. J. Broxterman; N. Feller; C. M. Kuiper; E. Boven; C. H. M. Versantvoort; T. T
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Article
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1995
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John Wiley and Sons
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French
⚖ 966 KB
## Abstract The contribution of P‐glycoprotein (Pgp) to multidrug resistance in human solid tumors is generally estimated from bulk mRNA measurements or immunohistochemistry, while direct measurement of the effect of Pgp on intracellular drug concentrations has not been pursued. We investigated the