(104) Peripheral nerve injury insult alters proteomic profile of the spinal dorsal horn synaptosome-associated proteins

Growth-associated protein 43 immunoreact

Growth-associated protein 43 immunoreactivity in the superficial dorsal horn of the rat spinal cord is localized in atrophic C-fiber, and not in sprouted A-fiber, central terminals after peripheral nerve injury

✍ Doubell, T.P.; Woolf, C.J. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 698 KB

Peripheral nerve injury induces the up-regulation in dorsal root ganglion cells of growth-associated protein 43 and its transport to the superficial laminae of the dorsal horn of the spinal cord, where it is located primarily in unmyelinated axons and growth-cone like structures. Peripheral nerve in