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1036 Radiosensitization of cells by trans-dominant inhibition of poly(ADP-ribosyl)ation

✍ Scribed by V. Rudat; J.-H. Köpper; K.J. Weber; M. Wannenmacher

Book ID
103726974
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
75 KB
Volume
32
Category
Article
ISSN
0360-3016

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## Abstract Poly(ADP‐ribosyl)ation is a post‐translational modification catalyzed by the enzyme family of poly(ADP‐ribose) polymerases (PARPs). PARPs exhibit pleiotropic cellular functions ranging from maintenance of genomic stability and chromatin remodeling to regulation of cell death, thereby re