103. Longitudinal study of thenar motor unit number estimates in amyotrophic lateral sclerosis patients
โ Scribed by X. Liu; J. Zhang; J. Zheng; S. Zhang; Y. Xu; D. Kang; D. Fan
- Book ID
- 119216738
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 46 KB
- Volume
- 119
- Category
- Article
- ISSN
- 1388-2457
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The following data were obtained on 21 amyotrophic lateral sclerosis (ALS) patients, aged 36-76 years (mean: 58 years), at baseline and months 4, 8, and 12: thenar motor unit number estimate (MUNE) using multiple point stimulation, mean thenar surface-recorded motor unit action potential negative-pe
The sequence of pathophysiological changes in amyotrophic lateral sclerosis (ALS) at the single motor unit (MU) level is not well understood. Using a recently described technique, a comprehensive range of physiological properties in two thenar MUs in ALS were intensively studied. In the first MU, de
## Abstract Limitations associated with global measures of function in patients with amyotrophic lateral sclerosis (ALS) and the qualitative nature of needle electromyography have stimulated the development of alternate means of monitoring disease severity and progression in ALS. Thus, the objectiv