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1-[(ω-Aminoalkyl)amino]-4-[ N -(ω-aminoalkyl)carbamoyl]-9-oxo-9,10-dihydro- acridines as Intercalating Cytotoxic Agents: Synthesis, DNA Binding, and Biological Evaluation

✍ Scribed by Antonini, Ippolito; Polucci, Paolo; Jenkins, Terence C.; Kelland, Lloyd R.; Menta, Ernesto; Pescalli, Nicoletta; Stefanska, Barbara; Mazerski, Jan; Martelli, Sante

Book ID
121388140
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
231 KB
Volume
40
Category
Article
ISSN
0022-2623

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ChemInform Abstract: 1-[(ω-Aminoalkyl)amino]-4- [N-(ω-aminoalkyl)carbamoyl]-9-oxo-9,10-dihydroacridines as Intercalating Cytotoxic Agents: Synthesis, DNA Binding, and Biological Evaluation.
✍ I. ANTONINI; P. POLUCCI; T. C. JENKINS; L. R. KELLAND; E. MENTA; N. PESCALLI; B. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

1-[(ω-Aminoalkyl)amino]-4-[N-(ω-aminoalkyl)carbamoyl]-9-oxo-9,10dihydroacridines as Intercalating Cytotoxic Agents: Synthesis, DNA Binding, and Biological Evaluation. -DNA-binding results from thermal denaturation and fluorescence-based studies are reported for the title compounds such as (III), ob