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1-Trifluoromethyl-1-diethoxyphosphoryl Carbene: A New Synthon for the Preparation of CF3-Containing α-Hydroxy and α-Amino Phosphonic Acid Derivatives.

✍ Scribed by Igor D. Titanyuk; Daria V. Vorob'eva; Sergej N. Osipov; Irina P. Beletskaya


Publisher
John Wiley and Sons
Year
2006
Weight
29 KB
Volume
37
Category
Article
ISSN
0931-7597

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A convenient preparation of derivatives
✍ D.S. Kemp; Wesley E. Stites 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 295 KB

The title compound has been prepared as its N-benzyloxycarbonyl urethane in a three-step one-pot reaction in 20-30% yield from the dipeptide derivative Z-Gln-Glu(OH)2. Evidence concerning the configuration and chiral purity of the title compound is given.