1 /T1p and Low-Field 1 / T1 of Tissue Water Protons Arise from Magnetization Transfer to Macromolecular Solid-State Broadened Lines
✍ Scribed by Rodney D. Brown III; Seymour H. Koenig
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 546 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
We argue that, for solutions of immobilized protein and for tissue, the dependence of 1 / T~1~ of solvent protons on B~0~ at low fields and 1 / T~1p~ on B~1~ for all B~0~ are both manifestations of the same underlying phenomena: magnetization transfer between mobile water protons and solid‐state broadened protein proton levels. Broadening causes rapid mixing of spin orientation within the transverse plane, at all B~0~, unless B~1~ is greater than the protein internal field; this affects 1 / T~1p~ of solvent protons by magnetization transfer. Similarly, decreasing B~0~ below the internal field mixes all orientations of magnetization, which affects the solvent proton low‐field 1 / T~1~ and high‐field 1 / T~2~.© 1992 Academic Press,Inc.