✦ LIBER ✦

1 Synthesis, mode of interaction with the enzyme and biological activities of a series of novel inhibitors of HIV-proteinase derived from penicillins

✍ Scribed by DC Humber

Book ID: 118393070
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 58 KB
Volume: 20
Category: Article
ISSN: 0166-3542
DOI: 10.1016/0166-3542(93)90379-w

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery and Analysis of a Series of C2

Discovery and Analysis of a Series of C2-Symmetric HIV-1 Proteinase Inhibitors Derived from Penicillin

✍ N.M. Gray; J.M. Cameron; N. Cammack; K.N. Cobley; D.S. Holmes; D.C. Humber; D.C. 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 569 KB

In order to identify a suitable peptide substrate for human immunodeficiency virus-1 (HIV-1) proteinase, a range of peptides from various cleavage sites within the gag-pol polyprotein were assayed by HPLC for specific cleavage. The peptide with the optimal combination of favorable kinetics and good

Synthesis and structure-activity relatio

Synthesis and structure-activity relationships of a series of penicillin-derived HIV proteinase inhibitors containing a stereochemically unique peptide isostere

✍ Holmes, Duncan S.; Bethell, Richard C.; Cammack, Nicholas; Clemens, Ian R.; Kitc 📂 Article 📅 1993 🏛 American Chemical Society 🌐 English ⚖ 951 KB

ChemInform Abstract: Synthesis and Struc

ChemInform Abstract: Synthesis and Structure-Activity Relationships of a Series of Penicillin-Derived HIV Proteinase Inhibitors Containing a Stereochemically Unique Peptide Isostere.

✍ D. S. HOLMES; R. C. BETHELL; N. CAMMACK; I. R. CLEMENS; J. KICHIN; P. MCMEEKIN; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

Structure-Based Design: Synthesis and Bi

Structure-Based Design: Synthesis and Biological Evaluation of a Series of Novel Cycloamide-Derived HIV-1 Protease Inhibitors

✍ Ghosh, Arun K.; Swanson, Lisa M.; Cho, Hanna; Leshchenko, Sofiya; Hussain, Khaja 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 287 KB

Novel, Potent, and Selective Phosphodies

Novel, Potent, and Selective Phosphodiesterase 5 Inhibitors: Synthesis and Biological Activities of a Series of 4-Aryl-1-isoquinolinone Derivatives

✍ Ukita, Tatsuzo; Nakamura, Yoshinori; Kubo, Akira; Yamamoto, Yasuo; Moritani, Yas 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 316 KB

Novel, Potent, and Selective Phosphodies

Novel, Potent, and Selective Phosphodiesterase-4 Inhibitors as Antiasthmatic Agents: Synthesis and Biological Activities of a Series of 1-Pyridylnaphthalene Derivatives

✍ Ukita, Tatsuzo; Sugahara, Masakatsu; Terakawa, Yoshihiro; Kuroda, Tooru; Wada, K 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 347 KB