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1. Partial mediation by endogenous prostaglandin E2 of the inhibition of osteocalcin production by cytokines but not by parathyroid hormone in osteoblast-like cells

โœ Scribed by Evans, D.B.; Thavarajah, M; Kanis, J.A.


Book ID
123272909
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
120 KB
Volume
11
Category
Article
ISSN
8756-3282

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The cytokine interleukin-6 (IL-6) was produced by neonatal mouse parietal bones during a 6- or 48-hour culture period in response to prostaglandin E2 (PGE2) and bovine parathyroid hormone (PTH) 1-34 fragment but not 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. At the same time there was an increase in ta