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1-O-Alkyl-2-acyl-sn-glycero-3-phosphocholine: A novel source of arachidonic acid in neutrophils stimulated by the calcium ionophore A23187

โœ Scribed by Charles L. Swendsen; J.Marshall Ellis; Floyd H. Chilton III; Joseph T. O'Flaherty; Robert L. Wykle


Book ID
115756465
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
481 KB
Volume
113
Category
Article
ISSN
0006-291X

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โœ Howard E. Wey ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 586 KB

Pretreatment of macrophages with 12-0-tetradecanoylphorbol-13-acetate (TPA) has been shown to enhance the release of arachidonic acid from cell phospholipids in response to agonist stimulation. This study describes the ability of TPA to also alter calcium ionophore A23 187-induced incorporation of [