1-cyano-5-methoxy-2-tetralone
✍ Scribed by Paul Grafen; Richard B. Turner
- Publisher
- Elsevier Science
- Year
- 1964
- Tongue
- French
- Weight
- 97 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
A synthesis of l-cyano-5-methoxy-2-tetralone (I) from 5-methoxy-2-tetralone via the hydroxymethylene derivative and the corresponding isoxazole, m.p. 137' , vma,(Nujol) 1658, 1605, 1580 cm.-', A,,(EtOH) 274 q_t(1,740), 280 ~(1,950), has recently been reported by Pellet&x and Parthasarathy (1).
📜 SIMILAR VOLUMES
In the title molecule, C 39 H 38 N 2 O 5 , the pyrrolidine ring is in an envelope conformation and the cyclohexyl ring adopts a chair conformation. The cyclohexanone ring in the tetralone moiety adopts a sofa conformation. The molecular packing in the crystal is stabilized by CÐHÁ Á Á% interactions
The title compound, C 17 H 12 Cl 2 O, has a cyclohexenone ring in the half-chair conformation. The aryl ring in the side chain attached to the tetralone ring is twisted out of the plane of the ,-unsaturated ketone plane as a result of non-bonded interactions.
The title compound, C 10 H 8 N 2 O 2 , consisting of a benzene ring with two OÐCH 2 ÐCN ortho substituents, has approximately C 2 symmetry. The supramolecular structure of the compound is determined by two hydrogen bonds and two %±% stacking interactions.