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1-Carbamoyl- and 1-aminomethyl-1,4-dihydropyrrolo[3,4-b]indole derivatives. Indole formation by fragmentation of strain-barrier stabilized 2-aminoindoline derivatives

✍ Scribed by Southwick, Philip L.; Vida, Julius A.; Fitzgerald, Berenice M.; Lee, Sung Ki


Book ID
121388742
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
832 KB
Volume
33
Category
Article
ISSN
0022-3263

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1,2-Bis(1H-indol-2-yl)ethane (9) has been prepared and converted into indolo[2,3-c]carbazole (8) using palladium acetate in refluxing acetic acid. Reaction of 9 with CoF 3 in hot TFA led to isolation of cyclohept[1,2-b:5,4-b H ]bisindole derivatives 11 and 12, which could be elaborated into further