Synthesis of (R)-(+)-1,2,3,6-tetrahydro-
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I. Victor Ekhato; Che C. Huang
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Article
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1995
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John Wiley and Sons
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French
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1,2,3,6-Tetrahydr0-4-[U-1~C]phenylpyridine (12) was synthesized and coupled to (R)-3-phenyl-3-cyclohexene-1-carboxylic acid to make the titled compound 2 in 21% overall yield. Purification considerations were an important factor in the choice of a reaction sequence to 2, and successful synthesis was