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1-Acetyl-3-(2,5-dichlorophenyl)-5-(4-fluorophenyl)-2-pyrazoline

✍ Scribed by Zhang, Yun-Chen

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
456 KB
Volume
63
Category
Article
ISSN
1600-5368

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✦ Synopsis

The title compound, C 17 H 13 Cl 2 FN 2 O, was prepared by the reaction of hydrazine and 1-(2,5-dichlorophenyl)-3-(4-fluorophenyl)-2-propenyl-1-ketone. In the molecule, the dihedral angle between the two benzene rings is 66.63 (9) . In the crystal structure, weak intermolecular C-HÁ Á ÁCl hydrogen bonds connect molecules into centrosymmetric dimers.

Related literature

The medicinal and biological properties of pyrazoline derivatives have been reported previously (

πŸ“œ SIMILAR VOLUMES

1-Acetyl-5-(4-chlorophenyl)-3-(4-fluorop
1-Acetyl-5-(4-chlorophenyl)-3-(4-fluorophenyl)-2-pyrazoline
✍ Guo, Huan-Mei ;Jian, Fang-Fang ;Zhao, Pu-Su ;Li, Li-Min ;Wu, Qian πŸ“‚ Article πŸ“… 2007 πŸ› International Union of Crystallography 🌐 English βš– 212 KB

In the title compound, C 17 H 14 ClFN 2 O, all bond lengths and angles show normal values. The two benzene rings make a dihehral angle of 82.17 (2) . Weak intermolecular C-HÁ Á ÁO hydrogen bonds stabilize the crystal packing.

1-Acetyl-5-(2,6-dichloroΒ­phenΒ­yl)-3-(2-n
1-Acetyl-5-(2,6-dichloroΒ­phenΒ­yl)-3-(2-naphthΒ­yl)-2-pyrazoline
✍ Lu, Zhi-Ke ;Li, Shen ;Huang, Peng-Mian πŸ“‚ Article πŸ“… 2006 πŸ› International Union of Crystallography 🌐 English βš– 163 KB

In the title compound, C 21 H 16 Cl 2 N 2 O, the pendant benzene ring and the naphthalene ring system make dihedral angles of 82.9 (3) and 6.7 (3) , respectively, with the central pyrazoline ring.

5-(4-Fluorophenyl)-3-(4-methylphenyl)-1-
5-(4-Fluorophenyl)-3-(4-methylphenyl)-1-phenyl-2-pyrazoline
✍ Guo, Huan-Mei πŸ“‚ Article πŸ“… 2007 πŸ› International Union of Crystallography 🌐 English βš– 488 KB

In the title compound, C 22 H 19 FN 2 , the mean plane of the pyrazoline ring forms dihedral angles of 18.52 (10) with the phenyl ring, 71.69 (10) with the fluorophenyl ring and 4.82 (10) with the p-tolyl ring.

3-(4-Chlorophenyl)-5-(4-fluorophenyl)-1-
3-(4-Chlorophenyl)-5-(4-fluorophenyl)-1-phenyl-2-pyrazoline
✍ Guo, Huan-Mei πŸ“‚ Article πŸ“… 2007 πŸ› International Union of Crystallography 🌐 English βš– 801 KB

In the title compound, C 21 H 16 ClFN 2 , the pyrazoline ring forms dihedral angles of 14.88 (11) with the phenyl ring, 74.59 ( 11) with the fluorophenyl ring and 7.16 (10) with the chlorophenyl ring.